Genome Sequencing and Annotation of <i>Bacillus subtilis</i> UBBS-14 to Ensure Probiotic Safety

Sulthana, Ayesha; Lakshmi, Suvarna G; Madempudi, Ratna Sudha

doi:10.7150/jgen.31170

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J Genomics 2019; 7:14-17. doi:10.7150/jgen.31170 This volume Cite

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Genome Sequencing and Annotation of Bacillus subtilis UBBS-14 to Ensure Probiotic Safety

Ayesha Sulthana^✉, Suvarna G Lakshmi, Ratna Sudha Madempudi

Center for Research and Development, Unique Biotech Limited, Hyderabad - 500 078, India

Citation:

Sulthana A, Lakshmi SG, Madempudi RS. Genome Sequencing and Annotation of Bacillus subtilis UBBS-14 to Ensure Probiotic Safety. J Genomics 2019; 7:14-17. doi:10.7150/jgen.31170. https://www.jgenomics.com/v07p0014.htm

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Abstract

Bacillus subtilis is a rod shaped, gram positive, spore producing bacterium. They are the normal flora of gastrointestinal tract of humans and it is the best characterized model organism for endospore formation. It has the ability to withstand environmental stress, and synthesize beneficial compounds, therefore, it is recognized as a high-quality probiotic supplement. To ensure the probiotic safety and the efficiency, we report the whole genome sequence (WGS) of Bacillus subtilis UBBS-14 strain. The draft genome sequence of Bacillus subtilis UBBS-14 consists of 4,048,984 bp and 4,017 genes, respectively. Bacillus subtilis UBBS-14 does not carry any antibiotic resistant genes containing plasmid, nor it contains any harmful putative virulence factors coding genes, therefore, it confirms the probiotic safety of the respective strain at genome level.

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APA

Sulthana, A., Lakshmi, S.G., Madempudi, R.S. (2019). Genome Sequencing and Annotation of Bacillus subtilis UBBS-14 to Ensure Probiotic Safety. Journal of Genomics, 7, 14-17. https://doi.org/10.7150/jgen.31170.

ACS

Sulthana, A.; Lakshmi, S.G.; Madempudi, R.S. Genome Sequencing and Annotation of Bacillus subtilis UBBS-14 to Ensure Probiotic Safety. J. Genomics 2019, 7, 14-17. DOI: 10.7150/jgen.31170.

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CSE

Sulthana A, Lakshmi SG, Madempudi RS. 2019. Genome Sequencing and Annotation of Bacillus subtilis UBBS-14 to Ensure Probiotic Safety. J Genomics. 7:14-17.

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