J Genomics 2017; 5:128-131. doi:10.7150/jgen.22393 This volume

Short Research Paper

Exploring Effects of Sex and Diet on Drosophila melanogaster Head Gene Expression

Maria D. L. A. Jaime1✉, Juan Hurtado2, 3, Mariana Ramirez Loustalot-Laclette2, Brian Oliver1, Therese Markow3, 4✉

1. Section of Developmental Genomics, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA;
2. Department of Ecology, Genetics and Evolution, IEGEBA (CONICET-UBA), Faculty of Exact and Natural Sciences, University of Buenos Aires, Ciudad Universitaria, C1428EHA, Buenos Aires, Argentina;
3. National Laboratory for the Genomics of Biodiversity, CINVESTAV, Irapuato, Guanajuato, Mexico;
4. Division of Biological Sciences, University of California San Diego, La Jolla CA 92093, USA.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
Jaime MDLA, Hurtado J, Loustalot-Laclette MR, Oliver B, Markow T. Exploring Effects of Sex and Diet on Drosophila melanogaster Head Gene Expression. J Genomics 2017; 5:128-131. doi:10.7150/jgen.22393. Available from https://www.jgenomics.com/v05p0128.htm

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Graphic abstract

Gene expression depends on sex and environment. We stringently explored the contributions of these effects in Drosophila melanogaster by rearing three distinct wildtype genotypes on isocaloric diets either high in protein or sugar followed by expression profiling of heads from the sexes. By using different genotypes as replicates we developed robust sex- and diet-biased expression responses.

Keywords: High protein diet, High sugar diet, Adult head, Drosophila melanogaster.